Milwaukee is the most populous city in the U.S. state of Wisconsin and the county seat of Milwaukee County. With a population of 577,222 at the …Milwaukee is the most populous city in the U.S. state of Wisconsin and the county seat of Milwaukee County. With a population of 577,222 at the 2020 census, Milwaukee is the 31st-most populous city in the United States and the fifth-most populous city in the Midwest. It is the central city of the Milwaukee metropolitan area, the 40th-most populous metro area in the U.S. with 1.57 million residents.
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