DNA damage and repair refers to the creation and correction of DNA lesions that threaten genome integrity. Because DNA replication errors or environmental agents that damage DNA can introduce ...

Guarding genes against damage is a crucial and complex job, so it’s to be expected that cells have several mechanisms to repair DNA breakages, each providing support under different circumstances.

This is a pipeline for the processing of imaging mass cytometry (IMC) data. It is largely based on Vito Zanotelli's pipeline. It performs image preprocessing and filtering, uses ilastik for ...

Our research is defining the normal mechanisms of DNA replication and repair, with the aim of understanding how it is deregulated in cancer cells. Maintaining the integrity of our DNA is central to ...

To combat this, all organisms possess highly conserved mechanisms to detect and repair DNA damage. Persistent DNA damage (genotoxic stress) triggers signaling cascades that drive cells into apoptosis ...

Genome instability can cause numerous diseases. Cells have effective DNA repair mechanisms at their disposal. A research team has now gained new insights into the DNA damage response. Whenever ...

This package is designed to facilitate the analysis workflow of mass cytometry data with automatic subset identification and mapping of cellular progression. Both command line and a GUI client are ...

Homologous recombination plays essential roles in the repair of DNA double strand breaks (DSBs) and collapsed replication forks. The fundamental reaction in homologous recombination is the exchange of ...

The genetic information itself is contained in a complex molecule called DNA which stands for deoxyribonucleic acid. Scientists worked out the structure of DNA in the 1950s. In 1951 Maurice ...

The Flow Cytometry platform at the University of Birmingham supports flow cytometry, cell sorting and mass cytometry across the University of Birmingham (UoB); the Technology Hub Flow Cytometry core ...

DNA is a short nickname for deoxyribonucleic (say: dee-OK-see-ri-bo-new-klee-ik) acid. DNA is the genetic information inside the body's cells that helps make people who they are. It's the instructions ...

The mass of an object tells you how heavy something is. You use grams (g) and kilograms (kg) to measure mass. Grams are used when you weigh a lighter item, like an apple or banana. Kilograms are ...