Morphine tolerance found to result from Tiam1-mediated maladaptive plasticity in spinal neurons
The spinal dorsal horn receives pain messages from peripheral areas of the body and relays them to the brain, or it can evoke ...
Chip Chick on MSN12d
The First Theropod Dinosaur Has Been Identified In Kyrgyzstan, And It Had What Appeared To Be A Protruding Eyebrow On Its Postorbital Bone, Indicating The Exist…
One of the most important groups of dinosaurs is the theropods from the Mesozoic Era. The group includes well-known predators ...
Nature4mon
Pain, plasticity, and premature birth: a prescription for permanent suffering?
Dorsal horn neurons receiving input from these terminals were hyperexcitable, demonstrating increased activity at rest and in response to tactile or noxious stimuli. This led to an increase in ...
Nature24d
The molecular basis of pain and its clinical implications in rheumatology
Serotonergic descending input provides control (both inhibition and facilitation) of dorsal horn nociceptive function. 32 Selective serotonin (5-hydroxytryptamine) reuptake inhibitors (SSRIs ...
Frontiers9d
Neuraxial Therapeutics in Pain Management: Present and Future
The neuraxial delivery of drugs has become a cornerstone in the management of pain, leveraging the pivotal roles of the dorsal root ganglion (DRG) and dorsal horn. These spinal structures are key in ...
BMJ11mon
Musculoskeletal pain and exercise—challenging existing paradigms and introducing new
TSP is a progressive increase in pain perception in the response to repeated stimuli of the same intensity and thought to represent central pain facilitation occurring at the dorsal horn neurons when ...
Mongabay27d
As a medicine, study finds rhino horn useless — and potentially toxic
Researchers say that efforts to reduce consumer demand for rhino horn products must run in parallel with protection. See All Key Ideas Fancy a taste of your own toenails? That’s what vendors in ...
The New York Times17d
Rebecca Horn, Enigmatic Artist With Theatrical Flair, Dies at 80
By Will Heinrich Rebecca Horn, an artist who channeled theatrical flair, a distinctive if paradoxically self-serious sense of humor and an undertone of dread into sculpture, performance ...
9 Adder Snake Species That Pack a Nasty Bite
Adder snakes are some of the most fascinating and misunderstood reptiles in the world. Known for their distinctive patterns and venomous bites, adders belong to the viper family and are native to ...
Fort Collins Coloradoan25d
Jimmy Horn Jr. says Colorado football team is taking Nebraska rivalry 'real serious'
Jimmy Horn Jr. had the best game of his college football career to open the 2024 season, but a bitter rivalry dating back to 1898 is all that's on his mind this week. The Colorado football team (1 ...
Artnet19d
3 Works by Pioneering Artist Rebecca Horn That Changed Contemporary Art
The German artist Rebecca Horn has died aged 80 in the town of Bad König on September 6, her foundation and gallery have confirmed. She is remembered for her visionary choreographies of body ...
Go full beast mode. Here are a few ways to tour the animal kingdom while keeping all your fingers.
Moose trample and sharks bite, but with the help of trained guides, that doesn’t mean they’re off limits to the ...