Normally, to infer evolutionary timelines, we would obtain a phylogeny of our species of interest with homologous genes, ...

Deletions and duplications of single-base pairs typically arise during homologous recombination and cause diseases. But what happens when a mutation occurs over multiple genes? Deletions involve ...

The typical process to create evolutionary timelines involves obtaining the phylogeny (evolutionary tree) of the concerned ...

Mutations in mammalian genes encoding homologous recombination proteins, including BRCA1, BRCA2 and PALB2, are associated with developmental abnormalities and tumorigenesis. Recent advances have ...

Much to our surprise, the same gene causes eyeless[ness] in the fruit fly. That came as a total surprise, because we thought that the fruit fly eye was in no way a homologous, a similar structure ...

Modalis Therapeutics Corporation (Tokyo Stock Exchange: 4883, CEO: Haru Morita), a leading company pioneering treatments for ...

Genetic testing of patients with prostate cancer and individuals who are at elevated risk for the disease has been slow to catch on.

The method also succeeded in silencing multiple homologous DELLA genes, addressing functional redundancy and enabling detailed analysis of gene roles in peach growth and development. "This method ...

The nucleus of a germline stem cell undergoes two divisions, firstly separating homologous chromosomes ... This is because the chromosomes - and genes - separate and are reshuffled during the ...

Importantly, we further study the homologous human genes as candidate genes for human anxiety disorders. The goal of our research is to facilitate development of targeted treatment of anxiety ...

Personalized Therapy Biosimulation Study Identifies Homologous Recombination Deficiency in Cancer Patients Beyond BRCA Status BARCELONA, Spain, September 16, 2024--(BUSINESS WIRE)--Cellworks Group Inc ...

New data show istisociclib (KB-0742) triggered cell death in preclinical ovarian cancer models of platinum and PARP-inhibitor (PARPi) ...