gingivalis translocation from the oral cavity to the pancreas using mouse models. By introducing the bacterium to genetically engineered mice predisposed to PDAC, the team uncovered compelling ...

Conclusion Direct conversion of the spleen into a liver-like organ, without cell or tissue transplantation, establishes fundamental hepatic functions in mice, suggesting its potential value for the ...

uk-halle.de Results Treatment with liposomal clodronate effectively reduced CD11b-positive macrophages both in the pancreas and other organs such as liver, lung and spleen. While tumour incidence and ...

The top of the left lobe of the liver, the left kidney, and the tail end of the pancreas are all in that same area. The ...

Diagram of the pancreas showing the different types of islet cells and the hormones they produce “To verify this, we produced mice in which, when they reach adulthood, all the non-beta cells in ...

Torso arteries Spleen organ vector illustration. Pancreas and surrounding organ and spleen detailed illustration on a white background. Beautiful colorful design intestinal medical digestive human ...

A team from the University of Geneva (UNIGE) has demonstrated the opposite: in adult mice whose pancreas contains only beta cells, glycaemia regulation and insulin sensitivity are even better than ...

Here, we describe that reduced C/EBPβ-LIP expression due to genetic ablation of the uORF delays the development of age-associated phenotypes in mice. Moreover, female C/EBPβ ΔuORF mice display an ...

The breakthrough was made by American researchers who injected diabetic mice with spleen cells from healthy animals. Apart from halting the disease, the treatment rebuilt the pancreas, a process ...

Until now, the scientific community agreed that beta cells needed the other hormone-producing cells of the pancreas to function properly. A team from the University of Geneva (UNIGE) has demonstrated ...

2018). These knock-in (KI) mice carry a serine to alanine mutation (S65A) in the N-terminal ubiquitin-like domain of the Park2 gene that encodes Parkin, a ubiquitin E3 ligase (McWilliams et al., 2018) ...

The pancreas plays a crucial role in digestion and controlling blood sugar levels. The six-inch-long organ sits behind the stomach and secretes enzymes that help the body digest proteins and ...