For this communication to occur, the presynaptic neuron releases a neurotransmitter, which is then received by a postsynaptic ...

So, if the presynaptic input is strong, the probability of obtaining a '1' as postsynaptic output will increase. In the extreme case, a very strong input will always make the postsynaptic neuron ...

A neuron-specific splice ... Neuroligin-1 is found on the postsynaptic side of excitatory synapses 5, and neurexins may be primarily localized to the presynaptic membrane, although definitive ...

Between impulses the transmitter molecules are rapidly removed from the synaptic cleft to prevent continuous stimulation of postsynaptic ... back into the presynaptic neuron and restored inside ...

Neurons have the amazing ability to self-organize into highly refined networks. I am interested in how these networks form. I am especially interested in the molecular pathways underlying this process ...

Dopamine’s effects in the brain are mediated by postsynaptic D1 and D2 receptors. Adenosine A1 and A2A receptors are uniquely positioned to counteract the excessive stimulation of dopamine receptors ...

At which specific step in synapse development is the activity of each protein required? How does a neuron maintain the correct balance of excitatory and inhibitory synapses in order to function ...

This increase in monoamine neurotransmitter concentrations results in increased binding at postsynaptic receptors ... their reabsorption into the presynaptic neuron. Drugs called monoamine ...

Studies on humans have generally been less definitive than those done on animals because it is substantially more difficult to record the activity of a single neuron in human brains. However ...

Amyotrophic lateral sclerosis (ALS) is a motor neuron disorder that manifests ... may be performed to distinguish between presynaptic and postsynaptic disorders. The panels are courtesy of Dr ...

The picture shows a cultured mouse hippocampal neuron. The small white dots are postsynaptic densities containing labelled FAM81A.

Neuroscience examines the structure and function of the human brain and nervous system. Neuroscientists use cellular and molecular biology, anatomy and physiology, human behavior and cognition ...