Chemically: there is a space (the synaptic cleft) between the axon terminus and the adjacent neuron. As the action potential reaches the end of the axon, a chemical is released that travels across the ...

Synaptic transmission consists of three steps: (1) intracellular vesicles loaded with neurotransmitters are targeted to the presynaptic membrane; (2) an action potential triggers exocytosis to release ...

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Wishing and hoping will not lead to neurons firing, axons being wrapped by myelin, synapses being activated, or neuronal ...

(3) This causes synaptic vesicles to fuse with the terminal ... (5) Ions flow into the postsynaptic neuron, which generates an action potential when a threshold level is reached.

Investigation of the biology of synaptic diseases will shed light on the molecular and cellular mechanisms that govern the function of the nervous system. It may also lead to the discovery of ...

Bioengineers and neuroscientists at the Wu Tsai Neurosciences Institute at Stanford University have developed a highly ...

The rate of action potential–evoked synaptic vesicle exocytosis was significantly decreased in LEMS treated neurones in comparison to neurones treated with control IgG. Spontaneous vesicular release ...

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The action of ammonia ... these findings bear a potential biochemical explanation for the multiple alterations of neurotransmitter receptor systems and of synaptic plasticity. Such changes may in part ...