RNA modulates transcription factor binding to DNA, though the subsequent effect on transcription remains unclear. The study ...

Every cell in our body contains the same DNA, yet liver cells are different from brain cells, and skin cells differ from ...

A new experimental method allows researchers to dissect how certain proteins, called pioneer factors, can bind to selective ...

The study stated that whereas vapers and smokers differ in various differentially methylated regions (DMRs), they share ...

Every cell in the human body has the same DNA, yet liver cells differ from brain cells, and skin cells from muscle cells.

For a while, it seemed like we had more computationally predicted sequence motifs without a known matching transcription factor, than transcription factors without a known binding sequence ...

Structural studies reveal the mechanism by which the mRNA nuclear export machinery engages with nascent transcripts through interaction with the cap binding complex.

NSD-2 is crucial for AR activity in prostate cancer, promoting tumor growth and offering a potential therapeutic target for advanced prostate cancer treatment.

Next, we performed motif analysis using DRIMust and MEME tools (see M ... Unlike Sfp1, no interaction was detected between these two transcription factors and the examined mRNAs (Fig. 3B, lower panels ...

and other motifs. The tool combs through the audio of each video and transcribes it, so it doesn’t factor in any visuals on the screen. However, after looking through the transcription, the program ...

"The sequence motif has a more potent influence on transcription than any DNA motif identified upstream of the transcriptional start site," Voichek explains. The motif is evolutionarily conserved ...