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    Alanine transaminase - Wikipedia

    Alanine transaminase (ALT), also known as alanine aminotransferase (ALT or ALAT), formerly serum glutamate-pyruvate transaminase (GPT) or serum glutamic-pyruvic transaminase (SGPT), is a transaminase enzyme (EC 2.6.1.2) that was first characterized in the mid-1950s by Arthur Karmen and colleagues. … See more

    ALT catalyzes the transfer of an amino group from L-alanine to α-ketoglutarate, the products of this reversible transamination reaction being pyruvate and L-glutamate.
    L-alanine + α-ketoglutarate ⇌ pyruvate + L-glutamate See more

    ALT is commonly measured clinically as part of liver function tests and is a component of the AST/ALT ratio. When used in diagnostics, it … See more

     
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  5. Alanine Aminotransferase (ALT) Test - StatPearls

    WEBFeb 27, 2024 — This review focuses on the significance of ALT in assessing hepatic injury and malfunction. ALT is aggregated primarily in the cytosol …

    • Author: Kevin E. Moriles, Samy A. Azer
    • Published: 2024/02/27
    • Publish Year: 2021
  6. Alanine Aminotransferase - The Definitive Guide

    WEBDec 6, 2020 — Alanine aminotransferase (ALT) is an enzyme produced primarily in liver and kidney cells but also found in smaller quantities in …

    • Estimated Reading Time: 10 mins
    • Inexpensive, Accurate, and Stable Method to Quantitate Blood …

    • Alanine Aminotransferase - an overview | ScienceDirect Topics

    • Alanine Aminotransferase - Medscape

      WEBSep 24, 2020 — ALT catalyzes the transfer of an amino group from alanine to a-ketoglutarate, the products of this reversible transamination reaction being pyruvate and glutamate, as seen in the formula below:...

    • Alanine Aminotransferase - an overview | ScienceDirect Topics

    • Alanine Transaminase (ALT) - Cleveland Clinic