Flunarizine is effective in the prophylaxis of migraine, occlusive peripheral vascular disease, vertigo of central and peripheral origin, and as an add-on in the treatment of epilepsy wh… See more

Flunarizine is contraindicated in patients with depression, in the acute phase of a … See more

The effects of other sedating drugs and alcohol, as well as antihypertensives, can be increased. No relevant pharmacokineticinteractions have been described.… See more

Mechanism of action
Flunarizine is a selective calcium antagonist with moderate other actions including antihistamine, serotonin receptor blocking an… See more

Flunarizine is a diphenylmethylpiperazine derivative related to the antihistamines hydroxyzine and cinnarizine(an older molecule also discovered by Janssen). See more