Placental tissues have become an established source of wound healing materials with use dating back to the early twentieth century. Placental tissue allografts have been used with significant benefits in surgery, the treatment of burns, chronic wounds, ophthalmology, and the management of diabetic foot ulcers.

Research has shown that placental-derived biomaterials can be used to promote wound healing by providing an ECM scaffold for tissue repair [ 4 ], exerting anti-inflammatory effects [ 4, 5, 6 ], facilitating cell migration [ 5, 6 ], and promoting regeneration [ 7 ].

The Epifix sterilised placental tissue used by Shah is processed from the amniotic membrane, or amnion, the innermost layer of the placenta. The amniotic membrane allograft, which comes in four sizes, is specifically designed for chronic and acute wound healing, as well as the reduction of inflammation and the formation of scar tissue.