‘Neuroglia’ or ‘glia’ are collective terms describing cells of neuroepithelial … See more

‘Astrocytosis’, ‘astrogliosis’, ‘reactive gliosis’, ‘astrocyte activation’, ‘astrocyte reactivity’, ‘astrocyte re-activation’, and ‘astrocyte reaction’ have been all used to describe astrocyte re… See more

Glial fibrillary acidic protein (GFAP)—a major protein constituent of astrocyte intermediate filaments—is the most widely used marker of reactive astrocytes (Table 1)12. Indeed… See more

Increased GFAP immunoreactivity largely reflects changes in the astrocytic cytoskeleton and tends to exaggerate the degree of hypertrophy because, with the exception o… See more

Research on astrocytes in CNS diseases has advanced in the last century in line with conceptual and technological progress in astrocyte biology. New approaches have been progre… See more