Scleroderma | Radiology Reference Article - Radiopaedia.org
Although presentation in childhood is indeed recognized 1, scleroderma is considered a disease of middle age (30-50 years of age) 3,4. There is a strong female predilection (F:M 3:1), even more pronounced during reproductive years (F:M 10:1) 2. 1. CREST syndrome 2. other connective tissue disorders 2.1. … See more
Clinical manifestation depends on which systems are predominantly involved. Approximately 60% (range 24-97%) develop an arthropathy that mostly affects the fingers, wrists, and ankles 3,5,6. … See more
These are best discussed under manifestations of individual systems. Please refer to respective subsections. See more
No cure for scleroderma exists. Treatment aims to reduce systemic involvement and target particular symptomatic organ systems. For targeted therapy, please refer to the articles that pertain to scleroderma and the particular body system. Systemic medication aimed at reducing the deposition of fibrous tissue and at reducing inflammation … See more
Subchondral Sclerosis? Causes, Symptoms, and Treatment ...
WEBSep 4, 2024 · The changes in bone linked to subchondral sclerosis show up on MRI and X-ray scans. The subchondral sclerosis appears as a bright, dense area of bone on the scans.
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Subchondral Sclerosis And Sclerosis Bone Lesions - OrthoNeuro
WEBOct 9, 2023 · Subchondral sclerosis is the thickening of the bone below the cartilage zone of joints. It most commonly affects the knee, hip, spine, and ankle joints. “Subchondral” …
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