Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine
WEBDec 10, 2020 — In an ongoing multinational, placebo-controlled, observer-blinded, pivotal efficacy trial, we randomly assigned persons 16 years of age or older in a 1:1 ratio to receive two doses, 21 days...
- Author: Fernando P. Polack, Stephen J. Thomas, Nicholas Kitchin, Judith Absalon, Alejandra Gurtman, Stephen ...
- Publish Year: 2020
See results only from nejm.orgEfficacy of the mRNA-1273 S…
At interim analysis in a phase 3, observer-blinded, placebo-controlled clinical trial, …
Phase 3 Safety and Efficacy …
In this ongoing, double-blind, randomized, placebo-controlled, phase 3 clinical trial, …
Efficacy of the mRNA-1273 SARS-CoV-2 Vaccine at Completion of …
WEBSep 22, 2021 — At interim analysis in a phase 3, observer-blinded, placebo-controlled clinical trial, the mRNA-1273 vaccine showed 94.1% efficacy in preventing coronavirus disease …
- Author: Hana M El Sahly, Lindsey R Baden, Brandon Essink, Susanne Doblecki-Lewis, Judith M Martin, Evan J An...
- Publish Year: 2021
Phase 3 Safety and Efficacy of AZD1222 (ChAdOx1 …
WEBSep 29, 2021 — In this ongoing, double-blind, randomized, placebo-controlled, phase 3 clinical trial, we investigated the safety, vaccine efficacy, and …
- Author: Ann R Falsey, Magdalena E Sobieszczyk, Ian Hirsch, Stephanie Sproule, Merlin L Robb, Lawrence Corey,...
- Publish Year: 2021
About Our Landmark Trial - Pfizer
WEBThe Phase 3 clinical trial was designed to determine if the Pfizer-BioNTech COVID-19 vaccine is safe and effective in preventing COVID-19 disease. This trial began July 27, 2020 and completed enrollment of 46,331 …
The clinical progress of mRNA vaccines and immunotherapies
WEBMay 9, 2022 — Most clinical applications of mRNA to date have focused on vaccines for infectious disease and cancer for which low doses, low protein expression and local …
Efficacy of COVID-19 vaccines: From clinical trials to real life
WEBDespite questions remain about the impact of virus variants and the duration of the immune response, messenger RNA (mRNA)-based and adenoviral vectored vaccines have …
Clinical development and approval of COVID-19 vaccines
WEBExpert Opinion. Despite unanticipated and complex challenges presented by real-time vaccine development in the context of the evolving COVID-19 pandemic and subsequent …
The COVID-19 Vaccine in Clinical Trials: Where Are We Now?
WEBThe results of clinical trials on COVID-19 vaccines. Up to now, a total of ten vaccine candidates have reported the results of human clinical trials, including four non …
Phase I/II study of COVID-19 RNA vaccine BNT162b1 in adults
WEBFeldman, R. A. et al. mRNA vaccines against H10N8 and H7N9 influenza viruses of pandemic potential are immunogenic and well tolerated in healthy adults in phase 1 …
Pfizer and BioNTech Conclude Phase 3 Study of COVID-19 …
WEBNov 18, 2020 — The Phase 3 clinical trial of BNT162b2 began on July 27 and has enrolled 43,661 participants to date, 41,135 of whom have received a second dose of the vaccine …
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